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What is an eBook?
An eBook is a print book that has been converted to an electronic format and made available for reading on your computer.

What is the difference between an eBook and a CaféScribe Digital Textbook?
The CaféScribe digital textbook is an eBook with multiple features, supporting multiple functionality that other eBooks do not have. For example, annotating and note sharing are two of the features found in CaféScribe digital textbooks but are not part of other eBooks.

— from http://support.cafescribe.com/Content/etextbook/etextbook_faq.htm

See also:
http://campustechnology.com/articles/2010/05/17/cafescribe-expands-social-networking-features.aspx

Follett has released an enhanced search and social networking update to its CaféScribe digital textbook platform.

CaféScribe is a Web-based system for finding and purchasing textbooks in digital format. After creating an account, the user can browse titles by various criteria, purchase selections through the online store or participating campus bookstore, and organize texts with provided thumbnail and listing tools. The latest version includes expanded search options for people or groups, plus support for sharing of notes, ideas, and documents between students, instructors, and the CaféScribe community.